浙江农业学报

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胰高血糖素样肽\|2在仔猪中的应用及其长效化研究进展

  

  1. (1 浙江师范大学 化学与生命科学学院,浙江 金华 321004; 2 浙江省农业科学院 畜牧兽医研究所,浙江 杭州 310021)
  • 出版日期:2015-02-25 发布日期:2015-03-12

Research progress of the application of glucagon\|like peptide\|2 on piglets and its half\|time prolongation strategy

  1. (1 College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua 321004, China; 2 Institute of Animal Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China)
  • Online:2015-02-25 Published:2015-03-12

摘要: 断奶应激引起的肠道形态及结构的破坏,导致仔猪出现腹泻、生长停滞等现象,严重危害着仔猪健康。胰高血糖素样肽\|2(GLP\|2)是一种多肽类胃肠激素,在促进肠道生长及损伤修复中起重要作用。文章分别综述了胰高血糖素样肽\|2的合成代谢、对仔猪肠道的保护作用及长效化应用,并对其在断奶仔猪上的应用作了展望。

关键词: 胰高血糖素样肽(GLP\, 2);断奶仔猪;肠道修复;长效化

Abstract: The injury of intestinal morphology and configuration induced by the weaning stress will cause diarrhea and growth cessation, which do harm to the health of piglets. Glucagon\|like peptide\|2 is an incretin gastrointestinal hormone, plays an important role in growth and restoration of intestines. This review summarized glucagon\|like peptide\|2 from anabolism, the therapeutic effects on intestinal injure of piglets and the half\|time prolongation strategy. The purpose of this paper is to provide references for further application of glucagon\|like peptide\|2 in weaning piglets.

Key words: glucagon\, like peptide\, 2, weaning piglet, intestinal restoration, half\, time prolongation