›› 2011, Vol. 23 ›› Issue (6): 0-1281.

• 综述 •    

抗菌肽及其应用前景概述

董世雷1,2,刘伟2,谢秀芝3,YU Hongwei4,王欣2,*
  

  1. 1浙江师范大学 化学与生命科学学院,浙江 金华 321004;2浙江省农业科学院 植物保护与微生物研究所,浙江 杭州 310021;3内蒙古工业大学 化工学院,内蒙古 呼和浩特 010051;4School of microbiology and immunology,Marshall University,Huntington 25755,USA
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-11-25 发布日期:2011-11-25

Overview of antimicrobial peptides and its application prospect

ONG Shilei;;LIU Wei;XIE Xiuzhi;YU Hongwei;WANG Xin;*   

  1. 1College of Chemistry and Life Science, Zhejiang Normal Univeristy,Jinhua [STBX]321004[STBZ],China;2Institute of Plant Protection and Microbiology,Zhejiang Academy of Agricultural Sciences,Hangzhou [STBX]310021[STBZ],China;3 College of Chemical Engineering, Inner Mongolia University of Technology,Hohhot [STBX]010051[STBZ],China;4School of Microbiology and Immunology,Marshall University,Huntington [STBX]25755[STBZ],USA
  • Received:1900-01-01 Revised:1900-01-01 Online:2011-11-25 Published:2011-11-25

摘要: 抗菌肽是生物体产生的一种具有抗菌活性的多肽类物质,它对细菌、真菌和病毒等都具有明显的杀伤作用。抗菌肽有望开发成为防治人和动物疾病的药物,应用前景广阔。文章对抗菌肽的结构特征、作用机制及应用前景进行了综述,以期为抗菌肽的更深层次的研究与应用提供参考。

关键词: 抗菌肽, 结构特征, 作用机制, 应用前景

Abstract: The antimicrobial peptides are a class of polypeptide substances with antimicrobial activity produced by organism and have a significant killing effect on bacteria, fungi, viruses, etc. Antimicrobial peptides have a wide application prospect and are expected to develop into the antibiotics candidates for the treatment, prevention and control of human and animal diseases. In this paper, the characteristics of structure, the mechanism of action and the application prospect of antimicrobial peptides were reviewed to provide a reference for its deeper research and application.

Key words: antibacterial peptide, characteristics of structure, mechanism of action, application prospect