›› 2013, Vol. 25 ›› Issue (4): 0-913.

• 论文 •    

MAP及其在动物营养与健康中的应用进展

许美芳1, 齐珂珂2, 胡向东1,*   

  1. 1 浙江皇冠科技有限公司,浙江 杭州 310012;2 浙江省农业科学院 畜牧兽医研究所,浙江 杭州 310021
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2013-07-25 发布日期:2013-07-25

Major acute phase protein and its application progress in animal nutrition and health

YU Mei-fang;QI Ke-ke;HU Xiang-dong;*   

  1. 1 Zhejiang Crown Technology Co., Ltd, Hangzhou 310012, China; 2 Institute of Animal Husbandry and Veterinary Sciences, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2013-07-25 Published:2013-07-25

摘要: MAP(major acute phase protein)是一种肝脏合成的急性期反应蛋白,分子量约为120 kDa,属于ITI(inter-α-trypsin inhibitor)家族。MAP与动物的营养和健康状态密切相关,研究表明机体MAP水平可反映动物的疾病状态及其严重程度,还可作为肉质与常规管理中动物福利的有效监测指标。文章综述了MAP的种类与结构特征及其合成过程,并进一步介绍了其在动物的营养与健康中的应用,就MAP在动物生产领域中的应用和研究重点及发展方向作了展望。

关键词: 主要急性蛋白(MAP), 急性期反应蛋白, 间-α-胰蛋白酶抑制剂(ITI), 动物健康

Abstract: Major acute phase protein (MAP) is one of the acute phase reactive proteins synthetized in liver, is a new plasma glycoprotein of 120 kDa belonging to inter-α-trypsin inhibitor (ITI) family. With close relation to animal nutrition and health, MAP can provide valuable diagnostic information about animal diseases and severity. Since muscular catabolism is associated to acute phase process, the determination of serum MAP concentration could be an effective parameter in meat inspection and animal welfare. The paper summarized the MAP classification, structural feature and synthetic process, also put emphasis on its application value in animal production field.

Key words: MAP, acute phase reactive protein, inter-α-trypsin inhibitor, animal health