›› 2010, Vol. 22 ›› Issue (5): 673-677.

• 论文 • 上一篇    下一篇

蛋白质序列的图形表示及相似性分析

强静,贺平安   

  1. 浙江理工大学 理学院, 浙江 杭州310018
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-09-25 发布日期:2010-09-25

Graphical representation of protein sequence and similarity analysis

QIANG Jing;HE Ping-an   

  1. College of Science, Zhejiang Sci-Tech University, Hangzhou 310018, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-09-25 Published:2010-09-25

摘要: 基于20个氨基酸的3个理化性质,给出了一种蛋白质序列的三维图形表示。在此基础上,进一步利用数学方法对所得到的蛋白质序列曲线进行了数值刻画;最后,基于这种数学描述,对9个不同物种的线粒体NADH脱氢酶进行了相似性分析。

关键词: 蛋白质序列, 图形表示, 数学描述, 相似性分析

Abstract: Based on three physical and chemical properties of twenty kinds of amino acids, a three-dimensional graphical representation of protein sequences was proposed in order to compare the similarity of protein sequences. Furthermore, the graphical representation curve was characterized by the mathematical descriptor. Then, the similarity analysis based on the mathematical descriptors of protein sequences was given for the mitochondrial NADH dehydrogenase protein sequences of nine different species.

Key words: protein sequences, graphical representation, mathematical descriptor, similarity analysis