›› 2012, Vol. 24 ›› Issue (4): 0-657.

• 论文 •    

细粒棘球绦虫miRNAs的鉴定及分析

郝力力1,李锐2,李必富1   

  1. 1西南民族大学 生命科学与技术学院, 四川 成都 610041; 2浙江省农业科学院 农产品质量标准研究所, 浙江 杭州 310021
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-07-25 发布日期:2012-07-25

Identification and analysis of miRNAs in Echinococcus granulosus

HAO Li-li;LI Rui;LI Bi-fu   

  1. 1College of Life Science and Technology, Southwest University for Nationalities, Chengdu 610041, China; 2 Institute of Quality and Standard for Agricultural Products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2012-07-25 Published:2012-07-25

摘要: 细粒棘球绦虫具有复杂的基因调控模式,在中间宿主和终末宿主体内具有截然不同的生物学特性。miRNA是真核生物内存在的非常重要的调控因子,本研究采用Solexa高通量测序技术,对G1株原头蚴microRNAs进行了鉴定和分析,总共发现了108条miRNAs,其中26条属于保守家族, 82条是细粒棘球绦虫特有。

关键词: 细粒棘球绦虫, miRNAs, Solexa高通量测序技术

Abstract: There exists complicated pattern of genes regulation in Echinococcus granulosus, which have distinct characteristics in definitive and intermediate hosts. miRNAs play important role of genes regulation in eukaryotic animals. There are one hundred and eight miRNAs were identified in this experiment and among of them twenty miRNAs belong to conserved miRNA families and eighty two are novel miRNAs in Echinococcus granulosus G1 strain.

Key words: Echinococcus granulosus, miRNAs, Solexa high-throughput sequencing technology