Abstract: Pleurotus eryngii is a very important edible and medical mushroom， whose fermented filtrates contain a lot of secondary metabolites. The inhibition effect of the fermented filtrates from Pleurotus eryngii on the growth of Alternaria alternata， Fusarium oxysporum f.sp.cucmrium and Fusarium graminearum was investigated. The results showed that the fermented filtrates from Pleurotus eryngii showed the lysis phenomenon and it had significant inhibition effects on pathogen mycelial growth and spore germination. The inhibitory rate of the extracts against the mycelial growth showed as Fusarium oxysporum f.sp.cucmrium （92.78%）>Alternaria alternata （89.76%）>Fusarium graminearum （87.45%） and the inhibitory rate against the spore germination were Fusarium graminearum （79.45%）>Alternaria alternata （72.25%）>Fusarium oxysporum f.sp.cucmrium （52.32%）. Therefore， there were the antipathogenic materials in fermented filtrates of Pleurotus eryngii， which could lay the foundation for the development of bioinhibitor.

Key words: fermented filtrates of Pleurotus eryngii, plant pathogenic fungi, inhibition effect