Abstract: To provide some basic information for high-yield cultivation，the influence of cultivation measures on the yield of purple cultivar from Dioscorea alata Linn. was studied by second order orthogonal rotative regression design and random block experiment. The results indicated that the order of influence on yield was the dosage of stock-tuber>planting density>the dosage of fertilizer，and there was significant interaction effects between the dosage of stock-tube and planting density. When the optimal cultivation measures were as follows：the dosage of stock-tuber from 67.60 g·plant^-1 to 76.80 g·plant^-1，planting density from 22 110 plant·hm^-2 to 23 760 plant·hm^-2，the dosage of fertilize from 1386 kg·hm^-2 to 1 578 kg·hm^-2，the yield would be over 28 000 kg·hm^-2.

Key words: Dioscorea alata Linn., design of second order orthogonal rotative regression, high-yield cultivation