Abstract: Triazole alcohols are used widely as disinfectants to prevent and treat the common pathogenic bacteria in plants, such as whip trichobacteria, basidiomycetes, imperfect fungi and so on. 2-(4-chlorine benzyl)-1-(1H-1,2,4-triazole-1-)-2-butylacohol was synthesized by Corey epoxidation from p-chloro benzene acetone, and by condensation with the 1H-1,2,4-triazole. The factors influencing the Corey-Chaykovsky epoxidation were studied and the yield was 97.9%. The optimum technological conditions of condensation were determined through orthogonal experiments. The optimum reaction conditions required that the molar ratio of the epoxide, 1H-1,2,4-triazole, and sodium bicarbonate was 1.0∶1.5∶2.1, the reaction temperature was 130℃, and the reaction time was 5 h. The condensation yield was above 82.0%．

Key words: triazole alcohol, 1H-1, 4-triazole, Corey-Chaykovsky epoxidation, condensation