浙江农业学报

• 动物科学 • 上一篇    下一篇

抗草甘膦转基因大豆粕对雄鼠运动机能的影响

  

  1. (1.暨南大学 生命科学技术学院,广东 广州 510632; 2.环境保护部 南京环境科学研究所,江苏 南京210042)
  • 出版日期:2016-07-25 发布日期:2016-07-08

Effects of glyphosateresistant transgenic soybean on physical enginery of male mice

  1. (1. College of Life Science and Technology, Jinan University, Guangzhou 510632, China; 2. Nanjing Institute of Environmental Sciences, Ministry of Environmental Protection, Nanjing 210042, China)
  • Online:2016-07-25 Published:2016-07-08

摘要: 在正常生理条件下,分别以抗草甘膦转基因大豆饲料和非转基因大豆饲料喂食雄性昆明小鼠,至30 d检测其运动能力、耐疲劳能力和耐缺氧能力,探讨抗草甘膦转基因大豆对雄鼠运动机能的影响。同时以环磷酰胺处理建立小鼠病理模型,探讨病理条件下抗草甘膦转基因大豆对雄鼠运动能力、耐疲劳能力和耐缺氧能力的作用。结果显示,在正常生理条件下,与非转基因对照组相比,喂食30 d抗草甘膦转基因大豆饲料组雄鼠的运动能力、耐疲劳能力和耐缺氧能力均无统计学差异(P>0.05);同样,在环磷酰胺诱导的病理条件下,喂食抗草甘膦转基因大豆饲料30 d也不会对雄鼠运动能力、耐疲劳能力和耐缺氧能力造成不良影响。结果表明,喂食抗草甘膦转基因大豆饲料30 d对雄鼠运动机能无毒性效应。

关键词: 转基因大豆, 小鼠, 运动机能, 环磷酰胺, 毒性效应

Abstract:  The effects of glyphosateresistant transgenic soybean on physical enginery were evaluated in male Kunming mice after being fed for 30 d with glyphosateresistant transgenic soybean and nontransgenic soybean, respectively. The locomotive ability, antifatigue and antianoxia ability were comparatively studied in both groups under normal physiological condition. The physical enginery was also tested in CPinduced pathological model of mice. Results showed that there were no significant differences of locomotive ability, antifatigue and antianoxia ability in both animal groups under normal physiological condition. Furthermore, compared with animals fed with traditional soybean, no significant differences of locomotive ability, antifatigue and antianoxia ability were observed in CPtreated pathological model animals fed for 30 d with glyphosateresistant transgenic soybean. In conclusion, there were no adverse toxicological effects of glyphosateresistant transgenic soybean fed for 30 d on physical enginery in male mice.

Key words: transgenic soybean, mice, physical enginery, cyclophosphamide, toxicological effect