Effect of masked T-2 toxin residues in Litopenaeus vannamei on routine blood and serum biochemical indexes of mice

doi:10.3969/j.issn.1004-1524.2017.07.08

›› 2017, Vol. 29 ›› Issue (7): 1110-1118.DOI: 10.3969/j.issn.1004-1524.2017.07.08

• Animal Science • Previous Articles Next Articles

Effect of masked T-2 toxin residues in Litopenaeus vannamei on routine blood and serum biochemical indexes of mice

HUANG Zhanrui¹, WANG Yaling^{1, *}, WANG Xiaobo¹, MO Bing², QIU Mei¹, SUN Lijun¹, CHEN Kangjian³, LIU Jian³

1. College of Food Science and Technology of Guangdong Ocean University, Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, Key Laboratory of Advanced Processing of Aquatic Products of Guangdong Higher Education Institution, Zhanjiang 524088, China;
2. Products Quality Supervising Test Institute of Guangxi Zhuang Autonomous Region, Nanning 530071, China;
3. Zhanjiang Hengxing Aquatic Product Science and Technology Co., Ltd, Zhanjiang 524088, China

Received:2017-01-15 Online:2017-07-20 Published:2017-07-24

Abstract

Abstract: After 20 d accumulation toxicity test of T-2 toxin, the free T-2 toxin in shrimp was quantitatively detected using LC-MS/MS. The shrimp head and muscle homogenate were administered to mice for 7 days, the blood routine and serum indexes in mice were detected to study the toxicity effect of residual masked T-2 toxin in Litopenaeus vannamei head and muscle on routine blood and serology of mice. The results showed that there was no free T-2 toxin in shrimp during 20 d accumulation toxicity test of T-2 toxin. And low-dose shrimp had no effect on mice. However, the high dose group shrimp caused an increase in neutrophils in mice, and erythrocyte system and platelet were significantly decreased (P<0.05). Moreover, serum biochemical indicators were significantly different (P<0.05). The damage of the head to the mice was higher than that of the muscle. Research showed that there was masked T-2 toxin in the infected shrimp, which had immune toxicity and blood toxicity to mice and led to the occurrence of inflammation, symptoms of anaemia, reduced the bone marrow hematopoietic function and damaged liver function. The damage of residual masked T-2 toxin in the head to the mice was higher than that of the muscle.

Key words: shrimp, masked T-2 toxin, routine blood, serum

CLC Number:

HUANG Zhanrui, WANG Yaling, WANG Xiaobo, MO Bing, QIU Mei, SUN Lijun, CHEN Kangjian, LIU Jian. Effect of masked T-2 toxin residues in Litopenaeus vannamei on routine blood and serum biochemical indexes of mice[J]. , 2017, 29(7): 1110-1118.

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Effect of masked T-2 toxin residues in Litopenaeus vannamei on routine blood and serum biochemical indexes of mice

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