Effects of glyphosate-resistant transgenic soybean on in vitro fertilization of male mice with reproductive damage

doi:10.3969/j.issn.1004-1524.2017.06.08

›› 2017, Vol. 29 ›› Issue (6): 910-916.DOI: 10.3969/j.issn.1004-1524.2017.06.08

• Animal Science • Previous Articles Next Articles

Effects of glyphosate-resistant transgenic soybean on in vitro fertilization of male mice with reproductive damage

LU Chunbin^1,2, ZHANG Yan¹, CHEN Bohui¹, LIN Zebin¹, QIU Pingle¹, LIU Biao^2,*

1. Department of Developmental & Regenerative Biology, Ji'nan University, Guangzhou 510632, China;
2. Nanjing Institute of Environmental Sciences, Ministry of Environmental Protection, Nanjing 210042, China

Received:2017-03-12 Online:2017-06-20 Published:2017-09-07

Abstract

Abstract: To assess the effects of glyphosate-resistant transgenic soybean on reproductive function in mice with reproductive damage male mice were injected chemotherapeutical agent, cyclophosphamide (CP), to induced reproductive damage as model mice. The formation rate of zygotes, 2-cells, 4-cells, 8-cells as well as blastocysts and excellent embryo rate were evaluated in vitro fertilization after feeding with glyphosate-resistant soybean for 30 days. The results showed that no significant difference (P> 0.05) in the formation rate of zygotes, 2-cells, 4-cells, 8-cells, as well as blastocysts and excellent embryo rate were observed in cyclophosphamide (CP) treated reproductive-damaged mice fed with glyphosate-resistant soybean for 30 days, compared with the mice fed with traditional soybean. In conclusion, there was no adverse effect on the reproductive function in male mice after feeding with transgenic soybean for 30 days under CP induced pathologic conditions.

Key words: transgenic soybean, mice, cyclophosphamide (CP), in vitro fertilization

CLC Number:

S816.42

LU Chunbin, ZHANG Yan, CHEN Bohui, LIN Zebin, QIU Pingle, LIU Biao. Effects of glyphosate-resistant transgenic soybean on in vitro fertilization of male mice with reproductive damage[J]. , 2017, 29(6): 910-916.

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Effects of glyphosate-resistant transgenic soybean on in vitro fertilization of male mice with reproductive damage

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