›› 2018, Vol. 30 ›› Issue (6): 932-938.DOI: 10.3969/j.issn.1004-1524.2018.06.07

• Animal Science • Previous Articles     Next Articles

Pathological study on duck-origin goose Parvovirus strain QH-L01 infection of Cherry Valley duck

CHEN Bing1, XU Jing1, 2, LUO Qihui1, 2, HUANG Chao1, LIU Wentao1, WU Hong2, CHEN Jingfei1, CHEN Ping1, GAO Qi1, MA Wenjing1, CHEN Zhengli1, 2, *   

  1. 1. Laboratory of Animal Disease Model, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China;
    2. Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China
  • Received:2017-09-25 Online:2018-06-20 Published:2018-07-02

Abstract: In the present study, the histopathological changes of various organs of Cherry Valley ducklings were explored under the condition of artificial infection, to clarify the pathogenesis and characteristics of duck-origin goose Parvovirus strain QH-L01. Thirty Cherry Valley ducks in experimental group were intramuscularly inoculated with 0.2 mL of 106.54 ELD50 duck-origin goose Parvovirus strain, and the ducks in the control group were intramuscularly inoculated with 0.2 mL of sterilized normal saline per duck, to observe the pathological changes of various tissues/organs in each infective stage at 1, 3, 6, 9 d, respectively. On the 1st day after infection, the lungs appeared punctate hemorrhage, partial lobular expansion, and intestinal tissue villous epithelial cells necrosed. On the 3rd day after infection, brain, kidney, thymus, bursa fabricius showed pathological changes, and villus of duodenum and ileum slight necrosed, mucosa layer of cecum appeared slight necrosis. On the 6th day after infection, lymphocytes in spleen increased, moderate necrosis was detected in villus of duodenum, ileum and mucosa layer of cecum. On the 9th day after infection, the lesions were reduced or returned to normal. The mortality rate was 20% during the whole infection period.

Key words: duck-origin goose Parvovirus, cherry valley duck, pathological change, damage

CLC Number: