大豆抗原蛋白对断奶仔猪生长性能及肠道免疫因子的影响

›› 2010, Vol. 22 ›› Issue (6): 843-847.

大豆抗原蛋白对断奶仔猪生长性能及肠道免疫因子的影响

张建中¹ , 卢建军^2,*

¹金华市婺城区畜牧兽医局,浙江金华321000；² 浙江大学饲料科学研究所,教育部动物分子营养学重点实验室,浙江杭州 310029

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-11-25 发布日期:2010-11-25

Effects of soybean antigen protein on the growth performance of weaning piglets

ZHANG Jian-zhong;LU Jian-jun;*

¹Wucheng Husbandry Bureau, Jinhua 321000,China;²Feed Science Institute, Zhejiang University, Hangzhou 310029, China

Received:1900-01-01 Revised:1900-01-01 Online:2010-11-25 Published:2010-11-25

摘要/Abstract

摘要： 以21日龄杜大长断奶仔猪为研究对象,探讨了大豆抗原蛋白对其生长性能和肠道免疫核因子的影响。结果表明,与对照组相比,试验组断奶仔猪日均采食量降低了25.88%(P<0.01)；日增重下降了28.70%(P<0.01),腹泻率提高了58.77%(P<0.01)；木糖吸收试验表明试验组仔猪在第1，2，3，4，5 h后血浆中木糖浓度分别比对照组低62.39%(P<0.01)，68.54%(P<0.01)，67.27%(P<0.01)，67.98%(P<0.01)和69.95%(P<0.01)；试验组断奶仔猪空肠和回肠组织绒毛长度分别降低27.56%(P<0.01)和22.43%(P<0.01),隐窝深度分别提高30.01%和53.03%(P<0.01)。十二指肠绒毛长度和隐窝深度差异不显著；空肠黏膜核因子NF-κB活性提高了71.87%(P<0.01)。结果提示,日粮中大豆抗原蛋白对断奶仔猪的生长性能产生了显著的负面影响,大豆抗原蛋白可能通过调控肠道黏膜组织核因子活性,影响了断奶仔猪肠道粘膜的形态和结构,进而影响采食量,腹泻率和生长性能。

关键词: 断奶仔猪, 大豆抗原蛋白, 生长性能, 核因子

Abstract: Forty\|eight piglets (Duroc×Large white×Landrace) weaned at 21 days were used to study the effects of soybean antigen protein on the growth performance in a period of 15 days. The results showed that soybean antigen protein significantly decreased AFI by 25.88%(P<0.01)and increased diarrhea rate by 58.77% (P<0.01) compared with the control group. The serum D\|xylose detection indicated that the serum D-xylose concentration was decreased by 62.39%(P<0.01), 68.54%(P<0.01), 67.27%(P<0.01), 67.98% (P<0.01) and 6995%(P<0.01) after 1, 2, 3, 4 h and 5 h respectively compared with the control group. The lengths of the villi within the jejunum and ileum tissues of the test group significantly decreased by 27.56% and 22.43% (P<0.01) and the crypt depth significantly increased by 30.01% and 53.03% (P<0.01) compared with the control group. There was no significant difference between duodenal villi length and crypt length. The activity of NF-κB in jejunum were increased 71.87%(P<0.01). The results indicated that soybean antigen protein in diet exerted a negative influence on growth performance of weaning piglets. Soybean antigen protein could regulate the nuclear factor activity of intestinal mucosa tissue, and affect the morphology and structure of intestinal mucosa tissue, furthermore, affect feed intake, diarrhea rate and growth performance of weaning piglets．

Key words: weaning piglets, soybean antigen protein, growth performance, nuclear factor kappa-B

张建中;卢建军;*. 大豆抗原蛋白对断奶仔猪生长性能及肠道免疫因子的影响[J]. , 2010, 22(6): 843-847.

ZHANG Jian-zhong;LU Jian-jun;*. Effects of soybean antigen protein on the growth performance of weaning piglets[J]. , 2010, 22(6): 843-847.

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