Abstract: Eimeria species were collected from five chicken farms in Shaoxing City， Zhejiang Province， and two anticoccidial drugs， i.e. Maduramicin and Diclazuril， were selected to test their drug resistance. The treatments were set as follows: Group 1 was infected with Eimeria oocysts and was medicated by Maduramicin; group 2 was infected with Eimeria oocysts and was medicated by Diclazuril; group 3 was infected with Eimeria oocysts yet was unmedicated; group 4 was uninfected and unmedicated. Drug resistance was assessed by ACI， POAA， RLS and ROP. The results revealed that all of the Eimeria species isolated were completely resistant to both Maduramicin and Diclazuril. It was suggested that the situation of drug resistance in chicken farms in Shaoxing City was serious. In order to avoid more economic loss， effective methods should be considered to control coccidiosis in this area.

Key words: Eimeria, Maduramicin, Diclazuril, drug resistance