Progress of genetic basis and regulatory mechanism of high temperature tolerance in rice

doi:10.3969/j.issn.1004-1524.20250187

Acta Agriculturae Zhejiangensis ›› 2025, Vol. 37 ›› Issue (11): 2426-2440.DOI: 10.3969/j.issn.1004-1524.20250187

• Review • Previous Articles Next Articles

Progress of genetic basis and regulatory mechanism of high temperature tolerance in rice

LI Xinxin¹^,²(), XU Heng², SONG Tao², YUAN Xi¹, SUN Meihao¹, ZHU Ying², ZHANG Hua²^,^*()

1. College of Life Science, Zhejiang Normal University, Jinhua 321004, Zhejiang, China
2. State Key Laboratory for Quality and Safety of Agro-Products, Research Center for Crop Molecular Breeding at Zhejiang Province, Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China

Received:2025-03-12 Online:2025-11-25 Published:2025-12-08

Abstract

Abstract:

Against the backdrop of global climate change, the frequent occurrence of high-temperature stress poses severe threat to rice production security and global food safety. Developing thermotolerant rice varieties represents a key strategy to address this challenge. This review systematically summarizes quantitative trait loci (QTL) and key genes associated with thermotolerance traits in rice, and provides an in-depth analysis of their regulatory mechanisms, to elucidate the genetic basis and molecular mechanisms underlying thermotolerance in rice. Based on the current research progress, this review outlines future research directions: 1) Conducting comprehensive analysis of the complex thermotolerance regulatory network in rice; 2) Systematically evaluating the effects of different thermotolerance genes in diverse genetic backgrounds to provide precise guidance for molecular breeding; 3) Establishing a scientific and comprehensive evaluation system for thermotolerant rice varieties.

Key words: rice, high temperature, quantitative trait loci (QTL) mapping, gene function, regulation mechanism

CLC Number:

S511

LI Xinxin, XU Heng, SONG Tao, YUAN Xi, SUN Meihao, ZHU Ying, ZHANG Hua. Progress of genetic basis and regulatory mechanism of high temperature tolerance in rice[J]. Acta Agriculturae Zhejiangensis, 2025, 37(11): 2426-2440.

Figures/Tables 2

Table 1 Quantitative trait locus(QTL) for heat tolerance in rice identified in recent years

亲本 Parents	遗传材料 Genetic material	QTL	所在染色体 Chromosome	所处位置 Marker/location	农艺性状 Agronomic trait	参考文献 Reference
IR64/N22	BC₅F₂	qHTSF4.1	4	M85-M83	小穗育性Spikelet fertility	[9]
IR64/Giza178,	F₂	qHTSF1.2	1	103.5-109.0 cM	小穗育性	[10]
Milyang23/Giza178		qHTSF2.1	2	4.8-19.8 cM	Spikelet fertility
		qHTSF2.2	2	43.0-63.0 cM
		qHTSF3.1	3	1.5-17.5 cM
		qHTSF4.1	4	66.0-73.0 cM
		qHTSF6.1	6	27.5-31.5 cM
		qHTSF11.2	11	25.3-42.3 cM
		qHTSF11.3	11	11.6-14.6 cM
IR64/N22	RIL	qSTIPSS9.1	9	SNP12393-12417	小穗育性Spikelet fertility	[8]
		qSTIPSS12.1	12	SNP14876-14892
		qSTIY3.1	3	SNP5308-5336	产量Yield
		qSTIY5.1	5	SNP8377-8401
Chikushi52/	BC₄F_3:4	qWB1	1	RM10870-RM7075	稻米垩白	[18]
Tsukushiroman		qWB3	3	RM3372-RM2791	White-back grains ratio
		qWB8	8	RM3181-RM3689
		qBW2	2	RM5470	稻米垩白Basal-white-grains
		qBW3	3	RM3372-RM2791
		qBW6	6	RM20429-RM6395
		qBW12	12	RM1986
		qGW2	2	RM5470-SNP2_1	粒重Grian weight
		qGW3	3	RM3372-RM2326
		qGW8	8	RM5556-RM3689
		qGW10	10	RM3373-RM1374
		qDTH3	3	RM3372-RM2326	抽穗期Days to heading
		qDTH12	12	SNP12_1-RM1986
Chikushi 52/	RIL	qMW2	2	RM5470	稻米垩白	[19]
Tsukushiroman		qMW4.1	4	RM16424	Milky white rice grains
		qMW4.2	4	RM6906
		qMW9	9	DdeI19
Sasanishiki/Habataki	CSSL	qSF^ht2	2	RM1234-RM3850	小穗育性Spikelet fertility	[11]
		qSF^ht4.2	4	RM3916-RM2431
		qPS $L h t$ 1	1	RM1196-RM6581	花粉发育
		qPSL^ht4.1	4	RM7585-Bb38P21a	Pollen shedding level
		qPSL^ht5	5	RM1248-RM4915
		qPSL^ht7	7	RM6394-RM1364
		qPSL^ht10.2	10	RM7492-RM1859
		qDFT3	3	RM3766-RM3513	开花时间Daily flowering time
		qDFT8	8	RM5891-RM4997
		qDFT10.1	10	RM6737-RM6673
		qDFT11	11	RM1355-RM2191
Sasanishiki/Habataki	CSSL	qHTB1	1	RM1387-RM8137	小穗育性Spikelet fertility	[12]
		qHTB3-1	3	RM4108
		qHTB3-2	3	RM5748-RM5864
		qHTB3-3	3	RM3525-RM6970
		qHTB4-1	4	RM7585-RM5633
		qHTB4-2	4	RM3534-RM2431
		qHTB5-1	5	RM1248-RM5579
		qHTB5-2	5	RM3236
		qHTB6	6	RM5963-RM3330
		qHTB10-1	10	RM3882-RM4455
		qHTB10-2	10	RM3773-RM6673
		qHTB11	11	RM286-RM7283
Hanaechizen/Niigatawase	RIL	qWB3	3	RM4383	稻米垩白White-back kernels	[20]
		qWB4	4	RM3288
		qWB6	6	RM8125
		qWB9	9	RM2482
		qKW3-1	3	RM7365	粒重Grian weight
		qKW3-1	3	RM3513
		qKW6	6	RM5314
		qKW7	7	RM505
		qKW10	10	RM2371
		qDH1	1	RM151	抽穗期Days to heading
		qDH3	3	RM5172
		qDH6	6	RM1369
R53/HHT4	BC₅F_3:4	qHTB1-1	1	RM11629-RM128	小穗育性Spikelet fertility	[13]
M9962/Sinlek	F₂	qSF1	1	34 280 000-34 420 000	小穗育性Spikelet fertility	[14]
		qSF2	2	18 730 000-19 100 000
		qSF3.1	3	26 120 000-26 220 000
		qSF3.2	3	28 730 000-28 960 000
Cheongcheong/Nagdong	DH	qSf3	3	RM15749-RM15689	结实率Spikelet fertility	[15]
		qSf4	4	RM1205-RM3330
		qSf8	8	RM23178-RM23191
		qTgw7	7	RM248-RM1134	千粒重1 000 grain weight
		qTgw8	8	RM149-RM23191
9311/ IRGC102309	BC₆F_3:4	qHTCGR5	5	RM1200-RM5796	稻米垩白Chalky grain rate	[23]
996/4628	RIL	qHTCGR1.1	1	RM297-RM6648	稻米垩白Chalky grain rate	[24]
		qHTCGR1.2	1	RM6648-RM6387
		qHTCGR3	3	SFP3_1-RM231
		qHTCGR6.1	6	RM3353-RM1369
		qHTCGR6.2	6	RM1369-RM190
		qHTCGR7.1	7	RM3859
		qHTCGR7.2	7	RM21327-RM21364
		qHTCGR7.3	7	RM21364-RM3859
Nipponbare/Kasalath	BIL	qHTAC6	6	R2689-R1962	直链淀粉含量	[22]
		qHTAC9-1	9	R1164-R1687	Amylose content
		qHTAC9-2	9	C506-G293
		qHTGC4	4	C1100-R1783	直链淀粉含量
		qHTGC6	6	L688-G200	Amylose content
		qHTGC7	7	C596-C213
		qHTGC8	8	G1073-R727
		qHTGC10	10	C1369-R1877
		qHTGC11	11	G257-R728
		qht-1	1	R1613-C970	粒重Grian weight	[21]
		qht-4	4	C1100-R1783
		qht-7	7	C1266-R1440
284 rice germplasms	水稻种质	qHTT1	1	Chr1_2646045	小穗育性Spikelet fertility	[16]
(189 indica and	Rice germplasms	qHTT3.1	3	Chr3_17441838
95 japonica)		qHTT3.2	3	Chr3_17758466
		qHTT4.1	4	Chr4_24524161
		qHTT4.2	4	Chr4_31476593
		qHTT5	5	Chr5_6246272
		qHTT7.1	7	Chr7_252305
189 indica rice materials		qHTT7.2	7	Chr7_24472878
		qHTT-X3.1	3	Chr3_18061266
		qHTT-X3.2	3	Chr3_20328744
		qHTT-X3.3	3	Chr3_21497502
		qHTT-X4	4	Chr4_31453877
		qHTT-X5	5	Chr5_6820123
		qHTT-X12	12	Chr12_15207279
173 rice materials	水稻种质	qSF5	5	Chr5_4668375	小穗育性Spikelet fertility	[17]
	Rice germplasms	qSF7	7	Chr7_28665880
		qRSF1	1	Chr1_19060745
		qRSF2	2	Chr2_23632215
		qRSF9.1	9	Chr9_9380313
		qRSF9.2	9	Chr9_22159984
		qRSF10	10	Chr10_14952621

Table 1 Quantitative trait locus(QTL) for heat tolerance in rice identified in recent years

亲本 Parents	遗传材料 Genetic material	QTL	所在染色体 Chromosome	所处位置 Marker/location	农艺性状 Agronomic trait	参考文献 Reference
IR64/N22	BC₅F₂	qHTSF4.1	4	M85-M83	小穗育性Spikelet fertility	[9]
IR64/Giza178,	F₂	qHTSF1.2	1	103.5-109.0 cM	小穗育性	[10]
Milyang23/Giza178		qHTSF2.1	2	4.8-19.8 cM	Spikelet fertility
		qHTSF2.2	2	43.0-63.0 cM
		qHTSF3.1	3	1.5-17.5 cM
		qHTSF4.1	4	66.0-73.0 cM
		qHTSF6.1	6	27.5-31.5 cM
		qHTSF11.2	11	25.3-42.3 cM
		qHTSF11.3	11	11.6-14.6 cM
IR64/N22	RIL	qSTIPSS9.1	9	SNP12393-12417	小穗育性Spikelet fertility	[8]
		qSTIPSS12.1	12	SNP14876-14892
		qSTIY3.1	3	SNP5308-5336	产量Yield
		qSTIY5.1	5	SNP8377-8401
Chikushi52/	BC₄F_3:4	qWB1	1	RM10870-RM7075	稻米垩白	[18]
Tsukushiroman		qWB3	3	RM3372-RM2791	White-back grains ratio
		qWB8	8	RM3181-RM3689
		qBW2	2	RM5470	稻米垩白Basal-white-grains
		qBW3	3	RM3372-RM2791
		qBW6	6	RM20429-RM6395
		qBW12	12	RM1986
		qGW2	2	RM5470-SNP2_1	粒重Grian weight
		qGW3	3	RM3372-RM2326
		qGW8	8	RM5556-RM3689
		qGW10	10	RM3373-RM1374
		qDTH3	3	RM3372-RM2326	抽穗期Days to heading
		qDTH12	12	SNP12_1-RM1986
Chikushi 52/	RIL	qMW2	2	RM5470	稻米垩白	[19]
Tsukushiroman		qMW4.1	4	RM16424	Milky white rice grains
		qMW4.2	4	RM6906
		qMW9	9	DdeI19
Sasanishiki/Habataki	CSSL	qSF^ht2	2	RM1234-RM3850	小穗育性Spikelet fertility	[11]
		qSF^ht4.2	4	RM3916-RM2431
		qPS $L h t$ 1	1	RM1196-RM6581	花粉发育
		qPSL^ht4.1	4	RM7585-Bb38P21a	Pollen shedding level
		qPSL^ht5	5	RM1248-RM4915
		qPSL^ht7	7	RM6394-RM1364
		qPSL^ht10.2	10	RM7492-RM1859
		qDFT3	3	RM3766-RM3513	开花时间Daily flowering time
		qDFT8	8	RM5891-RM4997
		qDFT10.1	10	RM6737-RM6673
		qDFT11	11	RM1355-RM2191
Sasanishiki/Habataki	CSSL	qHTB1	1	RM1387-RM8137	小穗育性Spikelet fertility	[12]
		qHTB3-1	3	RM4108
		qHTB3-2	3	RM5748-RM5864
		qHTB3-3	3	RM3525-RM6970
		qHTB4-1	4	RM7585-RM5633
		qHTB4-2	4	RM3534-RM2431
		qHTB5-1	5	RM1248-RM5579
		qHTB5-2	5	RM3236
		qHTB6	6	RM5963-RM3330
		qHTB10-1	10	RM3882-RM4455
		qHTB10-2	10	RM3773-RM6673
		qHTB11	11	RM286-RM7283
Hanaechizen/Niigatawase	RIL	qWB3	3	RM4383	稻米垩白White-back kernels	[20]
		qWB4	4	RM3288
		qWB6	6	RM8125
		qWB9	9	RM2482
		qKW3-1	3	RM7365	粒重Grian weight
		qKW3-1	3	RM3513
		qKW6	6	RM5314
		qKW7	7	RM505
		qKW10	10	RM2371
		qDH1	1	RM151	抽穗期Days to heading
		qDH3	3	RM5172
		qDH6	6	RM1369
R53/HHT4	BC₅F_3:4	qHTB1-1	1	RM11629-RM128	小穗育性Spikelet fertility	[13]
M9962/Sinlek	F₂	qSF1	1	34 280 000-34 420 000	小穗育性Spikelet fertility	[14]
		qSF2	2	18 730 000-19 100 000
		qSF3.1	3	26 120 000-26 220 000
		qSF3.2	3	28 730 000-28 960 000
Cheongcheong/Nagdong	DH	qSf3	3	RM15749-RM15689	结实率Spikelet fertility	[15]
		qSf4	4	RM1205-RM3330
		qSf8	8	RM23178-RM23191
		qTgw7	7	RM248-RM1134	千粒重1 000 grain weight
		qTgw8	8	RM149-RM23191
9311/ IRGC102309	BC₆F_3:4	qHTCGR5	5	RM1200-RM5796	稻米垩白Chalky grain rate	[23]
996/4628	RIL	qHTCGR1.1	1	RM297-RM6648	稻米垩白Chalky grain rate	[24]
		qHTCGR1.2	1	RM6648-RM6387
		qHTCGR3	3	SFP3_1-RM231
		qHTCGR6.1	6	RM3353-RM1369
		qHTCGR6.2	6	RM1369-RM190
		qHTCGR7.1	7	RM3859
		qHTCGR7.2	7	RM21327-RM21364
		qHTCGR7.3	7	RM21364-RM3859
Nipponbare/Kasalath	BIL	qHTAC6	6	R2689-R1962	直链淀粉含量	[22]
		qHTAC9-1	9	R1164-R1687	Amylose content
		qHTAC9-2	9	C506-G293
		qHTGC4	4	C1100-R1783	直链淀粉含量
		qHTGC6	6	L688-G200	Amylose content
		qHTGC7	7	C596-C213
		qHTGC8	8	G1073-R727
		qHTGC10	10	C1369-R1877
		qHTGC11	11	G257-R728
		qht-1	1	R1613-C970	粒重Grian weight	[21]
		qht-4	4	C1100-R1783
		qht-7	7	C1266-R1440
284 rice germplasms	水稻种质	qHTT1	1	Chr1_2646045	小穗育性Spikelet fertility	[16]
(189 indica and	Rice germplasms	qHTT3.1	3	Chr3_17441838
95 japonica)		qHTT3.2	3	Chr3_17758466
		qHTT4.1	4	Chr4_24524161
		qHTT4.2	4	Chr4_31476593
		qHTT5	5	Chr5_6246272
		qHTT7.1	7	Chr7_252305
189 indica rice materials		qHTT7.2	7	Chr7_24472878
		qHTT-X3.1	3	Chr3_18061266
		qHTT-X3.2	3	Chr3_20328744
		qHTT-X3.3	3	Chr3_21497502
		qHTT-X4	4	Chr4_31453877
		qHTT-X5	5	Chr5_6820123
		qHTT-X12	12	Chr12_15207279
173 rice materials	水稻种质	qSF5	5	Chr5_4668375	小穗育性Spikelet fertility	[17]
	Rice germplasms	qSF7	7	Chr7_28665880
		qRSF1	1	Chr1_19060745
		qRSF2	2	Chr2_23632215
		qRSF9.1	9	Chr9_9380313
		qRSF9.2	9	Chr9_22159984
		qRSF10	10	Chr10_14952621

Fig.1 Regulatory mechanisms of essential heat resistant genes in rice

References 70

[1]	CAMIGER S, VALLEE D. More crop per drop[J]. Rice Today, 2007(6):10-13.
[2]	PENG S B, HUANG J L, SHEEHY J E, et al. Rice yields decline with higher night temperature from global warming[J]. Proceedings of the National Academy of Sciences of the United States of America, 2004, 101(27): 9971-9975.
[3]	XU Y F, ZHANG L, OU S J, et al. Natural variations of SLG1 confer high-temperature tolerance in indica rice[J]. Nature Communications, 2020, 11: 5441.
[4]	LI X M, CHAO D Y, WU Y, et al. Natural alleles of a proteasome α2 subunit gene contribute to thermotolerance and adaptation of African rice[J]. Nature Genetics, 2015, 47(7): 827-833.
[5]	ZHANG H, ZHOU J F, KAN Y, et al. A genetic module at one locus in rice protects chloroplasts to enhance thermotolerance[J]. Science, 2022, 376(6599): 1293-1300.
[6]	LIU H Q, ZENG B H, ZHAO J L, et al. Genetic research progress: heat tolerance in rice[J]. International Journal of Molecular Sciences, 2023, 24(8): 7140.
[7]	XING Y H, LU H Y, ZHU X F, et al. How rice responds to temperature changes and defeats heat stress[J]. Rice, 2024, 17(1): 73.
[8]	PS S, SV A M, PRAKASH C, et al. High resolution mapping of QTLs for heat tolerance in rice using a 5K SNP array[J]. Rice, 2017, 10(1): 28.
[9]	YE C R, TENORIO F A, REDOÑA E D, et al. Fine-mapping and validating qHTSF4.1 to increase spikelet fertility under heat stress at flowering in rice[J]. Theoretical and Applied Genetics, 2015, 128(8): 1507-1517.
[10]	YE C R, TENORIO F A, ARGAYOSO M A, et al. Identifying and confirming quantitative trait loci associated with heat tolerance at flowering stage in different rice populations[J]. BMC Genetics, 2015, 16: 41.
[11]	ZHAO L, LEI J G, HUANG Y J, et al. Mapping quantitative trait loci for heat tolerance at anthesis in rice using chromosomal segment substitution lines[J]. Breeding Science, 2016, 66(3): 358-366.
[12]	ZHU S, HUANG R L, WAI H P, et al. Mapping quantitative trait loci for heat tolerance at the booting stage using chromosomal segment substitution lines in rice[J]. Physiology and Molecular Biology of Plants, 2017, 23(4): 817-825.
[13]	CAO Z B, LI Y, TANG H W, et al. Fine mapping of the qHTB1-1 QTL, which confers heat tolerance at the booting stage, using an Oryza rufipogon Griff. introgression line[J]. Theoretical and Applied Genetics, 2020, 133(4): 1161-1175.
[14]	NUBANKOH P, WANCHANA S, SAENSUK C, et al. QTL-seq reveals genomic regions associated with spikelet fertility in response to a high temperature in rice (Oryza sativa L.)[J]. Plant Cell Reports, 2020, 39(1): 149-162.
[15]	PARK J R, KIM E G, JANG Y H, et al. Screening and identification of genes affecting grain quality and spikelet fertility during high-temperature treatment in grain filling stage of rice[J]. BMC Plant Biology, 2021, 21(1): 263.
[16]	PAN Y H, CHEN L, ZHU X Y, et al. Utilization of natural alleles for heat adaptability QTLs at the flowering stage in rice[J]. BMC Plant Biology, 2023, 23(1): 256.
[17]	HU C M, JIANG J H, LI Y L, et al. QTL mapping and identification of candidate genes using a genome-wide association study for heat tolerance at anthesis in rice (Oryza sativa L.)[J]. Frontiers in Genetics, 2022, 13: 983525.
[18]	WADA T, MIYAHARA K, SONODA J Y, et al. Detection of QTLs for white-back and basal-white grains caused by high temperature during ripening period in Japonica rice[J]. Breeding Science, 2015, 65(3): 216-225.
[19]	MIYAHARA K, WADA T, SONODA J Y, et al. Detection and validation of QTLs for milky-white grains caused by high temperature during the ripening period in Japonica rice[J]. Breeding Science, 2017, 67(4): 333-339.
[20]	KOBAYASHI A, SONODA J, SUGIMOTO K, et al. Detection and verification of QTLs associated with heat-induced quality decline of rice (Oryza sativa L.) using recombinant inbred lines and near-isogenic lines[J]. Breeding Science, 2013, 63(3): 339-346.
[21]	朱昌兰, 肖应辉, 王春明, 等. 水稻灌浆期耐热害的数量性状基因位点分析[J]. 中国水稻科学, 2005, 19(2): 117-121.
	ZHU C L, XIAO Y H, WANG C M, et al. Mapping QTLs for heat tolerance during grain filling in rice[J]. Chinese Journal of Rice Science, 2005, 19(2): 117-121. (in Chinese with English abstract)
[22]	朱昌兰, 江玲, 张文伟, 等. 稻米直链淀粉含量和胶稠度对高温耐性的QTL分析[J]. 中国水稻科学, 2006, 20(3): 248-252.
	ZHU C L, JIANG L, ZHANG W W, et al. Identifying QTLs for thermo-tolerance of amylose content and gel consistency in rice[J]. Chinese Journal of Rice Science, 2006, 20(3): 248-252. (in Chinese with English abstract)
[23]	曹志斌, 李瑶, 曾博虹, 等. 非洲栽培稻垩白粒率耐热性QTL的定位[J]. 中国水稻科学, 2020, 34(2): 135-142.
	CAO Z B, LI Y, ZENG B H, et al. QTL mapping for heat tolerance of chalky grain rate of Oryza glaberrima Steud[J]. Chinese Journal of Rice Science, 2020, 34(2): 135-142. (in Chinese with English abstract)
[24]	张桂莲, 廖斌, 唐文帮, 等. 稻米垩白性状对高温耐性的QTL分析[J]. 中国水稻科学, 2017, 31(3): 257-264.
	ZHANG G L, LIAO B, TANG W B, et al. Identifying QTLs for thermo-tolerance of grain chalkiness trait in rice[J]. Chinese Journal of Rice Science, 2017, 31(3): 257-264. (in Chinese with English abstract)
[25]	ZHANG H, DUAN L, DAI J S, et al. Major QTLs reduce the deleterious effects of high temperature on rice amylose content by increasing splicing efficiency of Wx pre-mRNA[J]. Theoretical and Applied Genetics, 2014, 127(2): 273-282.
[26]	DONG N Q, SUN Y W, GUO T, et al. UDP-glucosyltransferase regulates grain size and abiotic stress tolerance associated with metabolic flux redirection in rice[J]. Nature Communications, 2020, 11: 2629.
[27]	KAN Y, MU X R, ZHANG H, et al. TT2 controls rice thermotolerance through SCT1-dependent alteration of wax biosynthesis[J]. Nature Plants, 2021, 8(1): 53-67.
[28]	LIU J P, ZHANG C C, WEI C C, et al. The RING finger ubiquitin E3 ligase OsHTAS enhances heat tolerance by promoting H₂O₂-induced stomatal closure in rice[J]. Plant Physiology, 2016, 170(1): 429-443.
[29]	TAKEHARA K, MURATA K, YAMAGUCHI T, et al. Thermo-responsive allele of sucrose synthase 3 (Sus 3) provides high-temperature tolerance during the ripening stage in rice (Oryza sativa L.)[J]. Breeding Science, 2018, 68(3): 336-342.
[30]	CAO Z B, TANG H W, CAI Y H, et al. Natural variation of HTH5 from wild rice, Oryza rufipogon Griff., is involved in conferring high-temperature tolerance at the heading stage[J]. Plant Biotechnology Journal, 2022, 20(8): 1591-1605.
[31]	WU N, YAO Y L, XIANG D H, et al. A MITE variation-associated heat-inducible isoform of a heat-shock factor confers heat tolerance through regulation of JASMONATE ZIM-DOMAIN genes in rice[J]. New Phytologist, 2022, 234(4): 1315-1331.
[32]	CHANDRAN A K N, SANDHU J, IRVIN L, et al. Rice Chalky Grain 5 regulates natural variation for grain quality under heat stress[J]. Frontiers in Plant Science, 2022, 13: 1026472.
[33]	SANDHU J, IRVIN L, CHANDARAN A K, et al. Natural variation in LONELY GUY-Like 1 regulates rice grain weight under warmer night conditions[J]. Plant Physiology, 2024, 196(1): 164-180.
[34]	CHEN K, GUO T, LI X M, et al. Translational regulation of plant response to high temperature by a dual-function tRNA^His guanylyltransferase in rice[J]. Molecular Plant, 2019, 12(8): 1123-1142.
[35]	GU X T, SI F Y, FENG Z X, et al. The OsSGS3-tasiRNA-OsARF3 module orchestrates abiotic-biotic stress response trade-off in rice[J]. Nature Communications, 2023, 14: 4441.
[36]	CHEN F, DONG G J, WANG F, et al. A β-ketoacyl carrier protein reductase confers heat tolerance via the regulation of fatty acid biosynthesis and stress signaling in rice[J]. New Phytologist, 2021, 232(2): 655-672.
[37]	WANG D, QIN B X, LI X, et al. Nucleolar DEAD-box RNA helicase TOGR1 regulates thermotolerant growth as a pre-rRNA chaperone in rice[J]. PLoS Genetics, 2016, 12(2): e1005844.
[38]	LI X T, TANG H S, XU T, et al. N-terminal acetylation orchestrates glycolate-mediated ROS homeostasis to promote rice thermoresponsive growth[J]. New Phytologist, 2024, 243(5): 1742-1757.
[39]	ZHANG P, ZHU W W, HE Y, et al. THERMOSENSITIVE BARREN PANICLE (TAP) is required for rice panicle and spikelet development at high ambient temperature[J]. New Phytologist, 2023, 237(3): 855-869.
[40]	LIU K W, WANG M N, WANG L J, et al. RMI1 is essential for maintaining rice genome stability at high temperature[J]. The Plant Journal, 2024, 120(5): 1735-1750.
[41]	SHE K C, KUSANO H, KOIZUMI K, et al. A novel factor FLOURY ENDOSPERM2 is involved in regulation of rice grain size and starch quality[J]. The Plant Cell, 2010, 22(10): 3280-3294.
[42]	TABASSUM R, DOSAKA T, ICHIDA H, et al. FLOURY ENDOSPERM11-2 encodes plastid HSP70-2 involved with the temperature-dependent chalkiness of rice (Oryza sativa L.) grains[J]. The Plant Journal, 2020, 103(2): 604-616.
[43]	AMBAVARAM M M R, BASU S, KRISHNAN A, et al. Coordinated regulation of photosynthesis in rice increases yield and tolerance to environmental stress[J]. Nature Communications, 2014, 5: 5302.
[44]	LIU X H, LYU Y S, YANG W P, et al. A membrane-associated NAC transcription factor OsNTL3 is involved in thermotolerance in rice[J]. Plant Biotechnology Journal, 2020, 18(5): 1317-1329.
[45]	CUI Y M, LU S, LI Z, et al. CYCLIC NUCLEOTIDE-GATED ION CHANNELs 14 and 16 promote tolerance to heat and chilling in rice[J]. Plant Physiology, 2020, 183(4): 1794-1808.
[46]	LO S F, CHENG M L, HSING Y C, et al. Rice Big Grain 1 promotes cell division to enhance organ development, stress tolerance and grain yield[J]. Plant Biotechnology Journal, 2020, 18(9): 1969-1983.
[47]	CHEN S Q, CAO H R, HUANG B L, et al. The WRKY10-VQ8 module safely and effectively regulates rice thermotolerance[J]. Plant, Cell & Environment, 2022, 45(7): 2126-2144.
[48]	QIAO B, ZHANG Q, LIU D L, et al. A calcium-binding protein, rice annexin OsANN1, enhances heat stress tolerance by modulating the production of H₂O₂[J]. Journal of Experimental Botany, 2015, 66(19): 5853-5866.
[49]	CAINE R S, YIN X J, SLOAN J, et al. Rice with reduced stomatal density conserves water and has improved drought tolerance under future climate conditions[J]. New Phytologist, 2019, 221(1): 371-384.
[50]	GANDASS N, KAJAL , SALVI P. Intrinsically disordered protein, DNA binding with one finger transcription factor (OsDOF27) implicates thermotolerance in yeast and rice[J]. Frontiers in Plant Science, 2022, 13: 956299.
[51]	HE Y, ZHANG X B, SHI Y F, et al. PREMATURE SENESCENCE LEAF 50 promotes heat stress tolerance in rice (Oryza sativa L.)[J]. Rice, 2021, 14(1): 53.
[52]	RANA R M, DONG S N, TANG H J, et al. Functional analysis of OsHSBP1 and OsHSBP2 revealed their involvement in the heat shock response in rice (Oryza sativa L.)[J]. Journal of Experimental Botany, 2012, 63(16): 6003-6016.
[53]	TANG Y Y, GAO C C, GAO Y, et al. OsNSUN2-mediated 5-methylcytosine mRNA modification enhances rice adaptation to high temperature[J]. Developmental Cell, 2020, 53(3): 272-286.e7.
[54]	GAO C, LU S, ZHOU R, et al. The OsCBL8-OsCIPK17 module regulates seedling growth and confers resistance to heat and drought in rice[J]. International Journal of Molecular Sciences, 2022, 23(20): 12451.
[55]	GUO M X, ZHANG X T, LIU J J, et al. OsProDH negatively regulates thermotolerance in rice by modulating proline metabolism and reactive oxygen species scavenging[J]. Rice, 2020, 13(1): 61.
[56]	LIU J P, SUN X J, XU F Y, et al. Suppression of OsMDHAR4 enhances heat tolerance by mediating H₂O₂-induced stomatal closure in rice plants[J]. Rice, 2018, 11(1): 38.
[57]	LI J J, YANG J, ZHU B H, et al. Overexpressing OsFBN1 enhances plastoglobule formation, reduces grain-filling percent and jasmonate levels under heat stress in rice[J]. Plant Science, 2019, 285: 230-238.
[58]	YAN Y, LI C, LIU Z, et al. A new demethylase gene, OsDML4, is involved in high temperature-increased grain chalkiness in rice[J]. Journal of Experimental Botany, 2022, 73(22): 7273-7284.
[59]	XU H, LI X F, ZHANG H, et al. High temperature inhibits the accumulation of storage materials by inducing alternative splicing of OsbZIP58 during filling stage in rice[J]. Plant, Cell & Environment, 2020, 43(8): 1879-1896.
[60]	HAKATA M, KURODA M, MIYASHITA T, et al. Suppression of α-amylase genes improves quality of rice grain ripened under high temperature[J]. Plant Biotechnology Journal, 2012, 10(9): 1110-1117.
[61]	KUSANO H, ARISU Y, NAKAJIMA J, et al. Implications of the gene for F1-ATPase β subunit (AtpB) for the grain quality of rice matured in a high-temperature environment[J]. Plant Biotechnology, 2016, 33(3): 169-175.
[62]	ZHANG H, XU H, FENG M J, et al. Suppression of OsMADS7 in rice endosperm stabilizes amylose content under high temperature stress[J]. Plant Biotechnology Journal, 2018, 16(1): 18-26.
[63]	SHEN C Q, ZHANG Y Y, LI G, et al. MADS8 is indispensable for female reproductive development at high ambient temperatures in cereal crops[J]. The Plant Cell, 2023, 36(1): 65-84.
[64]	CHEN C, BEGCY K, LIU K, et al. Heat stress yields a unique MADS box transcription factor in determining seed size and thermal sensitivity[J]. Plant Physiology, 2016, 171(1): 606-622.
[65]	LIAO M, MA Z M, KANG Y R, et al. ENHANCED DISEASE SUSCEPTIBILITY 1 promotes hydrogen peroxide scavenging to enhance rice thermotolerance[J]. Plant Physiology, 2023, 192(4): 3106-3119.
[66]	KIM S R, AN G. Rice chloroplast-localized heat shock protein 70, OsHsp70CP1, is essential for chloroplast development under high-temperature conditions[J]. Journal of Plant Physiology, 2013, 170(9): 854-863.
[67]	YANG X J, LI G, TIAN Y S, et al. A rice glutamyl-tRNA synthetase modulates early anther cell division and patterning[J]. Plant Physiology, 2018, 177(2): 728-744.
[68]	FAN Y R, ZHANG Q F. Genetic and molecular characterization of photoperiod and thermo-sensitive male sterility in rice[J]. Plant Reproduction, 2018, 31(1): 3-14.
[69]	YU H X, CAO Y J, YANG Y B, et al. A TT1-SCE1 module integrates ubiquitination and sumoylation to regulate heat tolerance in rice[J]. Molecular Plant, 2024, 17(12): 1899-1918.
[70]	ZHOU H F, WANG X L, HUO C M, et al. A quantitative proteomics study of early heat-regulated proteins by two-dimensional difference gel electrophoresis identified OsUBP21 as a negative regulator of heat stress responses in rice[J]. Proteomics, 2019, 19(20): e1900153.

Progress of genetic basis and regulatory mechanism of high temperature tolerance in rice

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

Figures/Tables 2

References 70

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	PEI Huimin, WU Mingming, ZHAI Rongrong, YE Jing, JIN Yue, ZHU Yi, HOU Jianjun, ZHU Guofu, YE Shenghai. Research progress on gene function and breeding of low-cadmium rice cultivars [J]. Acta Agriculturae Zhejiangensis, 2025, 37(9): 2012-2020.
[2]	TAN Shiyi, YU Guohong, XUE Xianglei, ZHAO Yinglei, XU Baoyu, ZHANG Chenghao. Design and experiment of tray handling device for industrialized rice seedling raising [J]. Acta Agriculturae Zhejiangensis, 2025, 37(7): 1545-1555.
[3]	ZHANG Zhi, HE Haohao, YU Miao, XU Jianfeng. Effects of chemical fertilizer reduction combined with soil conditioner on soil acidity, soil nutrients and rice yield [J]. Acta Agriculturae Zhejiangensis, 2025, 37(6): 1301-1308.
[4]	LIN Xiaobing, LI Jiang, CHENG Yanhong, WANG Binqiang, HE Shaolang, HUANG Shangshu, HUANG Qianru. Effects of organic materials on soil microbial biomass, mineral nitrogen content and rice yield [J]. Acta Agriculturae Zhejiangensis, 2025, 37(6): 1309-1318.
[5]	SU Yang, SHANG Xiaolan, QIAN Zhongming, WU Lingen, HUANG Jiaqi, ZHUANG Haifeng, ZHAO Yufei, DANG Hongyang, XU Lijun. Effects of synergistic enhancement of straw returning to the field with decomposition agent and biochar on soil quality and rice growth [J]. Acta Agriculturae Zhejiangensis, 2025, 37(5): 1139-1148.
[6]	ZHU Xiao, ZHU Ying, LI Hongjun, CHEN Shanfeng. Preparation and quality of oat chickpea compound rice by squeezing [J]. Acta Agriculturae Zhejiangensis, 2025, 37(5): 1149-1158.
[7]	LIU Qihua, SUN Zhaowen, ZHENG Chongke. Effects of nitrogen management on absorption and allocation of microelements in above-ground parts of dry direct-sowing rice [J]. Acta Agriculturae Zhejiangensis, 2025, 37(5): 987-997.
[8]	YING Yongfei, HAN Dongxuan, MENG Fang, YU Lin, SHEN Jialuan, WANG Kaiying. Effects of biogas slurry substituting chemical fertilizer on rice yield and quality and soil characteristics [J]. Acta Agriculturae Zhejiangensis, 2025, 37(4): 880-891.
[9]	SONG Xinlu, FAN Shuhong, WU Guangqi, ZHAN Mengqi, HOU Qian, LI Mingyue, XU Yan. Effects of combined copper-phenanthrene pollution on physiological characteristics and pollutant accumulation of rice roots at tillering stage [J]. Acta Agriculturae Zhejiangensis, 2025, 37(3): 521-529.
[10]	LEI Zhiwei, LI Xinxin, XU Heng, ZHANG Heng, ZHU Ying, ZHANG Hua. Identification of QTLs for stem borer resistance using chromosome segment substitution lines in rice [J]. Acta Agriculturae Zhejiangensis, 2025, 37(3): 530-537.
[11]	XIE Changyan, JIN Yumeng, ZHANG Miao, DONG Qingjun, LI Qing, JI Li, ZHONG Ping, CHEN Chuan, ZHANG Ankang. Application effect of nutrient soil made from river sludge for machine-transplanted rice seedling [J]. Acta Agriculturae Zhejiangensis, 2025, 37(3): 538-547.
[12]	LI Guiping, XU Xiaomei, LU Lizhi. Rice-duck farming and its environmental effects [J]. Acta Agriculturae Zhejiangensis, 2025, 37(3): 643-653.
[13]	WU Jiaqi, ZHU Xueming, BAO Jiandong, WANG Caoyi, ZHOU Xiaoyu, LI Lin, LIN Fucheng. Research progress on biological control of rice blast [J]. Acta Agriculturae Zhejiangensis, 2025, 37(3): 736-744.
[14]	WAN Shaoyuan, LIU Xianbo, CAI Shuo, SHI Hong, CHENG Jie. Effect of irrigation and planting methods on the yield and quality of double-cropping rice [J]. Acta Agriculturae Zhejiangensis, 2025, 37(2): 257-268.
[15]	LAN Xuecheng, ZHAO Fengliang, ZHANG Guangxu, LI Yang, GUO Xiaohong. Effects of nano zinc oxide and nano silicon dioxide on rice seed germination [J]. Acta Agriculturae Zhejiangensis, 2025, 37(2): 269-277.