Abstract: Gas chromatography (GC) method was developed for the determination of dimethyl fumarate(DMF)in food including drinks, biscuits and pickles sample. The effects of different extraction solvent, different extraction means and different chromatographic conditions were investigated. Samples could be extracted from food sample by chloroform and ultrasonic, and then were isolated by DB-FFAP column, detected by FID. The standard curve of DMF showed good linearity in the concentration range of 10-600 μg·mL-1 (r=0.9999). The detection limit of DMF was 0.072 mg·kg-1. The average recoveries of imazalil from three matrices at high and low levels ranged from 87.8% to 105.2% with DMF, and the repeat nature with relative standard deviations(RSD) was 2.4%-4.5%. In conclusions, this method is sensitive, simple accurate for the control of DMF in food．

Key words: dimethyl fumarate, gas chromatography, FID, food