浙江农业学报

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猪繁殖与呼吸综合征的抗病育种研究进展

  

  1. (1浙江农林大学 动物科技学院,浙江 临安 311300;2浙江青莲食品股份有限公司,浙江 嘉兴314000)
  • 出版日期:2014-09-25 发布日期:2014-10-11

Research progresses on the breeding of anti PRRS (porcine reproductive and respiratory syndrome) pigs

  1. (1 College of Animal Science and Technology, Zhejiang A & F university, Linan 311300, China;2 Zhejiang Qinglian Food Company Limited, Jiaxin 314000, China)
  • Online:2014-09-25 Published:2014-10-11

摘要: 猪繁殖与呼吸综合征(porcine reproductive and respiratory syndrome,PRRS)是近期危害养猪业最重要的疾病之一。培育抗病性品种是该病综合防治的一个有效方法。文章围绕该病抗病育种候选基因研究的主要进展进行综述,内容涉及病毒特异性受体基因、先天性免疫相关基因、抗原递呈信号通路相关基因、胞内miRNA等,并重点就今后PRRSV疾病耐受性和提高适应性免疫应答能力的研究进行展望。

关键词: 猪繁殖与呼吸综合征, 抗病育种, 候选基因, 疾病耐受性, 疾病抗性

Abstract: Anti\|disease breeding was effective on preventing infective disease in pigs. Recently, porcine reproductive and respiratory syndrome (PRRS) is severely impacted pig industry. Anti\|PRRSV (porcine reproductive and respiratory syndrome virus, PRRSV) breeding would be an effective solution. In the present paper, research progress on candidate genes for anti\|PRRSV breeding was summarized, including genes of virus receptor, innate immunology, antigen presentation signal pathway and miRNA. Moreover, further research focus on immune tolerance and adaptive immunology of PRRSV were suggested.

Key words: PRRS, anti\, disease breeding, candidate genes, disease tolerance, disease resistance