Abstract: To determine the optimum supplemental level of Taxus chinensis for broiler diet， this experiment was conducted to investigate the effects of paclitaxel on deposition in chicken and the Bcl\|2 gene expression. One hundred and eighty healthy broilers with similar weight （819±50） g were randomly allocated to 3 groups with 3 replicates per group and 20 chickens per replicate. Control group was fed with a basal diet， and test groups were fed with the basal diet supplemented with 1%， 3% dry powder of Taxus chinensis， respectively. The experiment lasted for 67 days. The results showed as follows: 1） The average daily gain and average daily feed intake of broilers fed diets with 3% Taxus chinensis were significantly lower than that in the control group during 1-30 day （P<001）. However， Taxus chinensis supplementation significantly improved the average daily gain and average daily feed intake of broilers during 31-60 day. The 1% group （P<005） and 3% group （P<001） all had higher average daily gain and average daily feed intake. The average daily gain and average daily feed intake of broilers were not significantly different between the control group and test group in the whole experiment period （P>005）. The ratio of feed to gain in all test groups were lower than that in the control group to some extent， while there were no significant differences among them （P>005）. 2） The paclitaxel in Taxus chinensis could deposit in breast muscle of broilers after feeding the diet supplemented with Taxus chinensis. The contents of paclitaxel in chicken increased from 0 to 062 ng·g-1. 3） Diet supplementation with 3% Taxus chinensis significantly up\|regulated the Bcl\|2 mRNA expression in liver （P<001）， but significantly down\|regulated the Bcl\|2 mRNA expression in lungs （P<001）. The Bcl\|2 mRNA expression in thymus and spleen were not significantly different between diets with 0% and 3% Taxus chinensis （P>005）. It is concluded that the paclitaxel in Taxus chinensis can be deposited in breast muscle of broilers after feeding the diet supplemented with Taxus chinensis， but the deposit amount is very low. The effects of 3% Taxus chinensis dry powder supplementation are better.

Key words: Taxus chinensis, paclitaxel, broilers, performance, Bcl\, 2